NeuroLacto
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    • Home
    • The team
    • Clinical Pilots
    • Nucleus
      • Articles
      • Science Behind
      • Oral-Motor Development ..
      • Neurophysiology of Inf ..
      • Early Indicators of Ne ..
      • Feeding Challenges in N..
      • Engineering Perspective
    • Roadmap
      • Equity
      • Versions
    • Awards & Certificates
NeuroLacto
  • Home
  • The team
  • Clinical Pilots
  • Nucleus
    • Articles
    • Science Behind
    • Oral-Motor Development ..
    • Neurophysiology of Inf ..
    • Early Indicators of Ne ..
    • Feeding Challenges in N..
    • Engineering Perspective
  • Roadmap
    • Equity
    • Versions
  • Awards & Certificates

The Science Behind NeuroLacto AI

The Problem

Quote from deck: “80% of preterm & 25–45% of term infants show early sucking difficulties, which can lead to various developmental disorders.” Cost statistic: “+22 NICU days ($66,000 extra per baby) due to challenges in neonatal nutrition and early feeding issues.”

How It Works

In just a 60-second recording, you can access 52 features powered by XGBoost AI, which provides an instant report covering maturity scores, risk predictions, and insights related to developmental disorders, neonatal nutrition, and sucking difficulties.

Validation & Performance

Version 1.0: Blind validation: 100% accuracy, κ = 1.000 (114 unseen infants) highlights the importance of assessing developmental disorders in early life. Early Version 2.0: >94% correlation with Bayley-III / Hammersmith at 4–6 months emphasizes the role of neonatal nutrition and its impact on infants experiencing sucking difficulties.

Roadmap

Version 1 → TRL 7 (live) addressing sucking difficulties related to developmental disorders.


Version 2 → TRL 6 (ongoing longitudinal) focusing on neonatal nutrition and its impact on infant development.


Version 3–7 → timeline to 24-month prediction for outcomes related to these factors.

Startups networking meetups: SNM01 Biomedical Engineerin

NeuroLacto AI:

An intelligent system for assessing infant feeding and sucking

performance using artificial intelligence to support early clinical decision-making


NeuroLacto.AI Recognized as the Best Presentation at the 1st Biomedical Startup Networking Meetup


NeuroLacto.AI was introduced at the 1st Biomedical Startup Networking Meetup, where the project was presented as a biomedical innovation focused on AI-supported assessment of infant feeding and sucking performance.

Payam Seyedkalateh presented the system’s clinical rationale, technological approach, and potential application in early neonatal feeding assessment. The presentation emphasized the role of objective sucking-pattern analysis in supporting early clinical decision-making, structured follow-up, and improved neonatal care pathways.

The presentation received outstanding feedback from both the audience and the organizing committee and was recognized as the best presentation of the day for its clarity, scientific depth, and strong real-world clinical relevance.

The meetup also provided an opportunity to engage in valuable discussions on technology commercialization, business development, and market-entry pathways in Oman and the GCC. These insights are highly relevant to NeuroLacto.AI’s next phase of development, including pilot implementation, strategic partnerships, and future clinical translation.

This recognition marks an important step in strengthening the visibility of NeuroLacto.AI as an emerging biomedical startup with the potential to contribute to early infant healthcare, digital health innovation, and AI-supported clinical assessment.

ISAA 2026: Intelligent Systems & AI Applications, Conference

    Beyond the Apgar Score:

    Interpretable Machine Learning Insights into Specialist Assessment of Infant Sucking and Feeding Adequacy 


    We were honored to participate in the International Conference on Intelligent Systems and Artificial Intelligence Applications (ISAA 2026), hosted by the University of Nizwa in Nizwa. This distinguished international conference brought together researchers, academics, and industry professionals to discuss recent advancements and emerging trends in intelligent systems and artificial intelligence.

    During the conference, we presented our work titled “Beyond the Apgar Score: Interpretable Machine Learning Insights into Specialist Assessment of Infant Sucking and Feeding Adequacy.” This study reflects a core part of the NeuroLacto vision—leveraging advanced, interpretable AI models to better understand infant feeding behaviors and support early, evidence-based clinical decision-making.

    Our participation provided a valuable opportunity to engage with a diverse audience of academics and practitioners from across disciplines. The discussions and feedback we received were both insightful and encouraging, reinforcing the importance of integrating artificial intelligence with neonatal care. It was particularly rewarding to see strong interest in how our approach moves beyond traditional assessment methods, such as the Apgar score, toward more dynamic and data-driven evaluation of infant feeding performance.

    The conference atmosphere fostered meaningful exchanges around innovation, collaboration, and real-world impact. Connecting with experts in AI, healthcare, and data science opened new perspectives for future development and potential partnerships. These interactions are essential as we continue refining NeuroLacto and expanding its applications in clinical and research settings.

    We are grateful to the organizers and collaborators who made this event possible, and we are proud to have shared our work on such a respected international platform. Participating in ISAA 2026 marks an important step forward in our journey to transform how infant feeding is assessed and understood.

    We look forward to building on the momentum from this experience and continuing to contribute to the intersection of artificial intelligence and maternal-infant health.

    Authors:

    Navid Nasiri, Payam Seyedkalateh,  Elnaz Pooralijani, Amna Al-Futaisi, Authaima AL-Farsi, Mohamed Abdellatif, and Abdulrahman Al Saadi 

    Link to the paper

    Discover the Magic of NeuroLacto

     The Hemtech Program stands as one of Oman’s most prestigious national initiatives for driving innovation and supporting high-impact projects aligned with the country’s vision for a knowledge-based economy. In its previous edition, Hemtech attracted over 400 participants from across the Sultanate, with top-selected projects receiving funding support of up to 40,000 Omani Rials to accelerate development and real-world impact.

    We are extremely proud to announce that NeuroLacto.AI was selected as the sole main winner of the latest Hemtech competition — the only project to secure this top position among all entries.

    The selection took place during a live event at Sultan Qaboos University (SQU), where the scientific evaluation team from Al-Jabar Company carefully assessed each team’s presentation, scientific foundation, innovation, originality, and potential for societal benefit. NeuroLacto.AI was chosen as the standout winner based on the strength of our vision, the rigor of our approach, and the clear potential to transform early infant assessment and improve postnatal and breastfeeding-related care.

    This achievement is a powerful validation of our team’s dedication and a major milestone in our mission to bring trustworthy, interpretable AI into neonatal and maternal healthcare.

    With the support and recognition from Hemtech, we are accelerating our efforts to bring these innovations closer to clinical practice — for better outcomes for newborns and mothers in Oman and beyond.

    Thank you to the Hemtech Program, Al-Jabar Company, Sultan Qaboos University, and everyone who contributed to this journey.



    #NeuroLactoAI #HemtechWinner #OmanInnovation #AIinHealthcare #NeonatalCare #SQU #AlJabarCompany

    Team members:

    Payam Seyedkalate, Navid Nasiri, Elnaz Pooralijani

    Three professionals stand in front of research posters at a conference or seminar.

    Real-Time Monitoring of Breastfeeding and Finger Sucking Pat

    Abstract

    Sucking and breastfeeding are essential for neonatal nutrition, providing vital nutrients that support optimal growth and immune system development. These activities also foster strong maternal-infant bonding, creating feelings of security and emotional comfort for the newborn. Furthermore, effective sucking patterns contribute to the infant's overall health, reducing risks of infections and promoting long-term well-being for both mother and child. Assessments of maternal health during pregnancy are crucial, as they reveal pre-existing conditions, nutritional status, and potential risks that could affect breastfeeding outcomes. For instance, factors like gestational diabetes, depression, or medication use can hinder breastfeeding initiation and maintenance, leading to early cessation in 30–50% of cases. Regular prenatal evaluations allow for early identification of complications, enabling timely interventions to support successful breastfeeding. Oral motor skills, including sucking and swallowing, are foundational for feeding efficiency and are closely linked to later speech and language development. Delays in these skills may signal neuromotor issues, increasing the risk of developmental vulnerabilities such as autism spectrum disorder or motor delays. Monitoring sucking patterns from birth can help detect subtle deficits that traditional subjective tools like LATCH or NOMAS often miss, with reliability estimates as low as 50–70%. In Oman, exclusive breastfeeding rates are low at 23% for the first six months, exacerbated by cultural preferences for formula feeding due to early work return and misinformation. Literature highlights the predictive value of sucking patterns: abnormal patterns correlate with developmental disorders (Yardımcı-Lokmanoğlu et al., 2024), while non-nutritive sucking matures with postmenstrual age and forecasts neurodevelopment (Martens et al., 2024; Vijay et al., 2023). Dose-response relationships show longer breastfeeding durations enhancing language skills and intelligence (Lovcevic, 2023; Oddy et al., 2011), with exclusive breastfeeding protecting against speech delays (Novayelinda et al., 2019; Dee et al., 2007). However, standardized tools for real-time sucking assessment are lacking, particularly in regions like Oman with high preterm rates (10% of births). The Smart Infant Sucking Tool (SIST) addresses this gap as a portable device measuring intraoral pressure, suck–swallow–breathe (SSB) coordination, and sucking frequency. By providing objective, real-time data, SIST enables early detection of feeding and developmental issues in primary health care settings, supporting Omani neonates and aligning with national health priorities.

    Authors

    Payam Seyedkalateh, Abdulrahman Al-Saadi, Elnaz Pooralijani, Hanan Saud Al-Maawali, Amna Al Futaisi, Authima Al Farsi, Navid Nasiri

    Link to the paper
    Three people giving a presentation in a conference room.

    NeuroLacto AI Presentation at Fursatech

    We are pleased to share that NeuroLacto AI was also presented at Fursatech, where the project was selected for presentation before the Scientific Committee.

    Fursatech provided an important platform for showcasing innovative ideas and emerging technology-based solutions with strong academic, technical, and societal value. Being selected to present NeuroLacto AI to the Scientific Committee was a meaningful recognition of the project’s scientific relevance, innovation potential, and interdisciplinary strength.

    At NeuroLacto AI, our work focuses on developing an AI-assisted system for infant sucking assessment to transform neonatal feeding evaluation into a more objective, data-driven, and clinically useful process. Presenting this concept at Fursatech allowed us to communicate both the engineering foundation of the system and its potential impact in maternal and neonatal healthcare.

    The opportunity to discuss NeuroLacto AI in front of the Scientific Committee was especially valuable, as it reflected confidence in the project not only as a startup or innovation concept, but also as a research-based solution with meaningful future applications.

    Participating in events such as Fursatech continues to strengthen our vision and motivates us to further develop NeuroLacto AI at the intersection of biomedical engineering, artificial intelligence, and clinical innovation.

    We are grateful for the opportunity to share our work and for the recognition received through this selection.

    Team members:

    Payam Seyedkalate, Navid Nasiri, Elnaz Pooralijani

    29.10.2025

    The published paper in 2022

    A Pilot Study of Developing an Infant Sucking Tester Instrum

    Abstract

     Objectives: Most preterm infants experience oral feeding disorder. Sucking is the most appropriate way for oral feeding, but it may be immature in preterm infants. Regarding the increased risk of feeding problems in preterm infants, investigating and monitoring their sucking patterns to present appropriate and timely intervention is recommended. The current research aimed to report the design of an instrument for measuring the suction pressure in preterm infants through a pilot study. We also checked the validity and reliability of the instrument. Methods: A pilot study was conducted to measure the validity and reliability of this instrument. First, the instrument was developed, and in the next step, discriminant validity, test-retest reliability, and comparison in terms of sex were investigated by measuring the suction pressure of 20 full-term and 15 preterm infants. The Mann-Whitney U test and Wilcoxon test were used to assess discriminant validity, sex-based comparisons, and test-retest reliability in SPSS v. 23. Results: Two groups showed a significant difference in the suction pressure (P<0.001) to support the discriminant validity of the instrument. We obtained satisfactory test-retest reliability in two groups (r=0.97, P<0.001). Boys and girls did not significantly differ between full-term (P=0.9) and preterm infant groups (P=0.5). Discussion: Performing the pilot study on 35 infants through an infant sucker tester proved the instrument’s discriminant validity and test-retest reliability. However, conducting the studies with a larger sample size is essential to make this instrument available commercially. 

    Authors

    Mehdi Dehghan, Payam Seyedkalateh, Zahra Akbarian-Rad, Mohsen Haghshenas Mojaveri, Soraya Khafri, Akram Ahmadi 

    Link to the paper

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